DEVELOPMENT OF TECHNOLOGY OF PRODUCTION AND QUALITY ASSESSMENT OF DRUG SUBSTANCE " DRY EXTRACT OF SCUTELLARIA ISCANDERI L. WITH SILVER NANOPARTICLES"

This study demonstrates the results of experimental studies aimed at development technology and assessment quality drug substance containing a dry extract flavonoid-containing herb silver nanoparticles, as well optimal technological parameters phytosynthesis process methods for qualitative quantitative content biologically active substances have been developed. Phytosynthesis nanoparticles was carried out using plant extracts, in which substances, flavonoids, act an agent that reduces ions to nanoparticles. The production chosen sample obtained t =50 °C ratio extract: nitrate = 1:4 one. Additionally, expiration date determined regulatory documentation. During assessment, it found should be least 2 mg/g. As result, became possible produce used preparation local antibacterial antifungal drugs treatment skin diseases.